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AI agent for laboratory technicians

Reagent Lot Qualification Agent

Show with recorded data that a new reagent lot performs like the old lot before it is used for real samples.

Quality controlManagementHealthcareScience and researchOperations
See how it worksGet access
Reagent Lot Qualification Agent: what goes in, what the agent does and what you get

What it does

A new reagent lot can shift results slightly, and the shift is only noticed after patient or sample results drift. This agent starts when a new lot is logged. It picks the qualification samples and controls required by the lab's procedure, tells the technician what to run, and reads the results from the instrument file. It compares the new lot to the old lot and to control ranges using the lab's tolerances, looking at bias and spread, not just pass or fail. If a result is outside tolerance, it requests a rerun, checks for obvious errors such as a wrong calibrator or expired material, and compares again. It records the outcome in the lot log. It never releases a lot. The lead approves use. Edge case: a shift in one level only is flagged for a closer look.

How it works

Follow the arrows from top to bottom. The orange dashed arrow is the loop: when a check fails, the agent goes back and tries again.

Start and resultWhat it doesA check on its own workWaits for your OKGoes back and retries
Yes, continueYes, continueApprovedNoNo 1 STARTS WHEN New lot logged 2 USES A TOOL Look up the procedure and select samples andcontrols 3 DOES Tell the technician which runs to perform 4 USES A TOOL Read the new lot and old lot results from theinstrument files 5 DOES Calculate bias and spread against the tolerance 6 CHECKS THE RESULT Are all levels within tolerance? If not: check calibrator, expiry and run notes, thenrequest a rerun. Back to step 4. 7 CHECKS THE RESULT Do the reruns agree with the first run? If not: mark the lot as failing and recommend contactingthe supplier. Back to step 4. 8 DOES Write the qualification record 9 YOU APPROVE Lead approves the lot for use 10 RESULT Lot released or rejected in the log
Read the steps as a list
  1. New lot logged
  2. Look up the procedure and select samples and controls
  3. Tell the technician which runs to perform
  4. Read the new lot and old lot results from the instrument files
  5. Calculate bias and spread against the tolerance
  6. Are all levels within tolerance?If not: check calibrator, expiry and run notes, then request a rerun. Back to step 4.
  7. Do the reruns agree with the first run?If not: mark the lot as failing and recommend contacting the supplier. Back to step 4.
  8. Write the qualification record
  9. Lead approves the lot for useThe agent waits here for your OK.
  10. Lot released or rejected in the log

How it decides

It accepts a lot only if the mean difference to the old lot and the control results are within the lab's tolerance at every level tested.

  • Reject a lot if bias exceeds the tolerance at any level
  • Request one rerun before failing a lot
  • Flag a lot where only one level shifts for lead review
  • Require at least the number of samples the procedure sets

Make it yours

Every agent is a starting point. You choose these settings for your own situation.

  • Tolerance per analyte (default 3% bias)
  • Number of qualification samples
  • Controls and levels
  • Rerun limit (default 1)
  • Record format

What keeps you in control

It always asks you first

  • Releasing the lot for use
  • Rejecting a lot and contacting the supplier

Hard limits

  • Never mark a lot in use
  • Keep every raw result with the record

It stops when

  • Done: the lot passes and is approved, or is rejected with a record
  • Stop: material is missing for the required runs

Set it up

We guide you through the set-up, step by step

Members get the full set-up guide for this agent. No technical skills needed: you copy, paste and upload.

10 minto set it up in your AI
5 AIsChatGPT, Claude, Copilot, Gemini, Grok
  • One set of instructions to paste into your AI, with the clicks for ChatGPT, Claude, Microsoft 365 Copilot, Gemini and Grok
  • The agent then walks you through connecting your own data, one source at a time
  • A downloadable copy with the flow chart, the rules and the full guide
Get access to this agent

An example run

What happensLot B-4417 of a glucose reagent was run on 20 qualification samples. Mean bias was 1.8% against a 3% tolerance, but the low control read 5.2% high. The agent requested a rerun, found a calibrator had expired the day before, and asked for a fresh one. The second run showed 1.1% bias, and the lead approved the lot.

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