NSF launches $1.5 billion X-Labs program to fund independent research teams on AI imaging and quantum systems

NSF launched X-Labs, a $1.5 billion program funding independent research teams in AI imaging and quantum systems over 10 years. Teams operate outside standard university structures, controlling their own hiring, budgets, and research direction.

Categorized in: AI News Science and Research
Published on: May 19, 2026
NSF launches $1.5 billion X-Labs program to fund independent research teams on AI imaging and quantum systems

NSF launches $1.5 billion program to fund independent research teams

The National Science Foundation announced NSF X-Labs, a $1.5 billion initiative over the next decade to fund independent research teams working on platform technologies. The program targets AI-enabled scientific imaging, quantum systems, and other areas the government considers national priorities.

The initiative differs from traditional NSF funding. Teams operate outside standard university, industry, and grant structures, with full control over hiring, budgets, research direction, and intellectual property.

How the funding works

NSF will use Other Transaction contract awards instead of standard federal procurement contracts. Teams selected for Phase 0 receive up to $1.5 million over 9 to 12 months. Those passing a Phase 1 review move into a 24 to 36-month period with funding up to $50 million per year.

The structure emphasizes speed. NSF requires that research, partnership, and organizational decisions happen "in days not weeks." Teams cannot need approval from a parent institution to allocate funding, change direction, hire staff, or negotiate contracts.

Initial research areas

The first two topic areas are:

  • Scientific Instrumentation for Sensing and Imaging: Teams will develop new scientific instruments using quantum sensing, AI-driven computational imaging, and new chemical modalities.
  • Quantum Systems: Interconnects and Integrated Photonics: Teams will create components for transferring quantum information and integrating different quantum systems.

NSF says additional topic areas will be announced in the coming weeks.

What applicants need to show

Proposals are capped at eight single-sided pages. Applicants must demonstrate they can operate with substantial independence-what NSF calls the Autonomy Factor Test. Teams must control decision-making, staffing, partnerships, research direction, contracting, and day-to-day operations.

Domestic organizations can submit proposals, with one lead organization holding the contract for each selected X-Lab. The deadline for current submissions is May 14, 2028, at 3 p.m. EDT.

For researchers interested in understanding how AI applies to scientific discovery and research automation, AI for Science & Research covers relevant skills and certifications.


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