Protein Structure Prediction Triage Agent

Structure prediction tools give fast protein models, but confidence varies by region, and a model can look convincing where it is really a guess. When sequences are submitted, this agent runs predictions for the proteins or variants and reads the confidence scores region by region. It compares predictions with any known structures. It then checks whether the regions that matter, such as active sites or mutation positions, are well predicted. If they are not, it tries alternative settings or templates and checks again, stopping after a set number of tries. It writes a short summary for experiment planning that marks reliable and unreliable regions. The biochemist decides how to use the models. Edge case: a mutation that sits in a low-confidence loop is flagged so nobody over-interprets its predicted effect.